ABSTRACT
Organ-on-a-chip is a three-dimensional microfluidic system that simulates the cellular structure and biological milieu of an organ, that seemed to be constructed and studied substantially in the last decade. Microchips can be configured to suit disease states in a variety of organs, including the lung. When contrasted to traditional in vitro models like monolayer cell lineages, lung-on-a-chip models lays out a pragmatic portrayal of disease pathophysiology and pharmaceuticals' mode of action, and this is especially more prevailing in connection with the COVID-19 pandemic. Animal models have typically been used in pharmaceutical drug screening to assess pharmacological and toxicological reactions to a new entity. These adaptations, on the other hand, do not precisely represent biological reactions in humans. Present and prospective uses of the lung-on-a-chip model in the pulmonary system are highlighted in this overview. In addition, the constraints of existing in vitro systems for respiratory disease simulation and therapeutic discovery would be emphasized. Attributes of lung-on-a-chip transformative features in biomedical applications will be addressed to illustrate the relevance of this lung-on-chip model for medical science.Copyright © 2022
ABSTRACT
Coronavirus is the most challenging threat today in our society. This virus has caused a huge number of deaths worldwide. Experts are still searching for an effective and long-term vaccine. In the present scenario, people are relying on wearing mask, self-quarantine, social-distancing and sanitizing hands for defending this infectious coronavirus. The health-care units, academicians, researchers and governments as well as business houses are trying their level best to prevent the spread of this disease. In this paper, design and implementation of an Internet of Things (IoT)-based smart and cost-effective system for tracking and monitoring of COVID-19 suspected patients have been introduced. Proposed system has significant social impact as it can be used to reduce the chances of community transmission of this deadly virus. Proposed reusable cost-effective system can help the hospital and local authority to monitor and track the movement of quarantined people. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
ABSTRACT
COVID-19 pandemic has been spread over a large geographical area and has affected a large proportion of the population. Maintaining social distance, quarantine, frequent hand-washing, using alcohol-based hand sanitizer and wearing medical mask are essential to protect us and others from COVID-19. To safe the people and help the government authority, several researchers have also developed many mobile applications, medical masks, drones, ventilation systems, etc. for this purpose. In this paper, an efficient android-application-controlled car for human safety against COVID-19 pandemic has been proposed. The proposed architecture can be useful for patient handling and proper transportation of COVID-19-suspected patients. This approach will be beneficial for the ambulance drivers and other emergency service providers who are playing an important role to protect the community from this infectious disease. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.